F11R anticorps

N° du produit ABIN2191795

Cet anticorps Rat Monoclonal détecte spécifiquement F11R dans WB, FACS, IP et IF. Il présente une réactivité envers Souris et a été mentionné dans 1 publication.

Aperçu rapide pour F11R anticorps (ABIN2191795)

Antigène: F11R (F11 Receptor (F11R))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp F11R est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: BV12

Détail du produit anti-F11R anticorps

Réactivité croisée (Details): Cross reactivity: Human : No

Stérilité: 0.2 μm filtered

Isotype: IgG2a

Information d'application

Indications d'application: For flow cytometry and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.

Références pour anticorps anti-F11R (ABIN2191795)

Martinez-Estrada, Manzi, Tonetti, Dejana, Bazzoni: "Opposite effects of tumor necrosis factor and soluble fibronectin on junctional adhesion molecule-A in endothelial cells." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 288, Issue 6, pp. L1081-8, (2005) (PubMed).

Détails sur F11R

Antigène: F11R (F11 Receptor (F11R))

Autre désignation: Junctional Adhesion Molecule-A

Sujet: The monoclonal antibody BV12 recognizes junctional adhesion molecule-A (JAM-A), also known as JAM-1 and the mouse platelet F11-Receptor (F11R), is a cell adhesion molecule (CAM). JAM-A is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-A belongs together with JAM-B (VE-JAM or JAM- 3) and JAM-C (JAM-2) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-A plays a role in platelet aggregation, secretion, adhesion and spreading. Aliases JAM-1, platelet F11-Receptor, F11R

Pathways: Cell-Cell Junction Organization